Antagonizing peroxisome proliferator‐activated receptor γ facilitates M1‐to‐M2 shift of microglia by enhancing autophagy via the LKB1–AMPK signaling pathway

Microglia‐mediated neuroinflammation plays a dual role in various brain diseases due to distinct microglial phenotypes, including deleterious M1 and neuroprotective M2. There is growing evidence that the peroxisome proliferator‐activated receptor γ (PPARγ) agonist rosiglitazone prevents lipopolysacc...

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Detalles Bibliográficos
Autores principales: Ji, Juan, Xue, Teng‐Fei, Guo, Xu‐Dong, Yang, Jin, Guo, Ruo‐Bing, Wang, Juan, Huang, Ji‐Ye, Zhao, Xiao‐Jie, Sun, Xiu‐Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052482/
https://www.ncbi.nlm.nih.gov/pubmed/29740932
http://dx.doi.org/10.1111/acel.12774

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052482/
https://www.ncbi.nlm.nih.gov/pubmed/29740932
http://dx.doi.org/10.1111/acel.12774

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