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Activation of DNA demethylases attenuates aging‐associated arterial stiffening and hypertension

DNA methylation increases with age. The objective of this study was to investigate whether compound H, a potential activator of DNA demethylases, attenuates aging‐related arterial stiffness and hypertension. Aged mice (24–27 months) and adult mice (12 months) were used. Pulse wave velocity (PWV), a...

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Detalles Bibliográficos
Autores principales: Chen, Kai, Sun, Zhongjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052484/
https://www.ncbi.nlm.nih.gov/pubmed/29659128
http://dx.doi.org/10.1111/acel.12762