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Overexpression of Nmnat3 efficiently increases NAD and NGD levels and ameliorates age‐associated insulin resistance

Nicotinamide adenine dinucleotide (NAD) is an important cofactor that regulates various biological processes, including metabolism and gene expression. As a coenzyme, NAD controls mitochondrial respiration through enzymes of the tricarboxylic acid (TCA) cycle, β‐oxidation, and oxidative phosphorylat...

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Detalles Bibliográficos
Autores principales: Gulshan, Maryam, Yaku, Keisuke, Okabe, Keisuke, Mahmood, Arshad, Sasaki, Tsutomu, Yamamoto, Masashi, Hikosaka, Keisuke, Usui, Isao, Kitamura, Tadahiro, Tobe, Kazuyuki, Nakagawa, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052485/
https://www.ncbi.nlm.nih.gov/pubmed/29901258
http://dx.doi.org/10.1111/acel.12798