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Human electronegative LDL induces mitochondrial dysfunction and premature senescence of vascular cells in vivo

Dysregulation of plasma lipids is associated with age‐related cardiovascular diseases. L5, the most electronegative subfraction of chromatographically resolved low‐density lipoprotein (LDL), induces endothelial dysfunction, whereas the least electronegative subfraction, L1, does not. In this study,...

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Detalles Bibliográficos
Autores principales: Wang, Yu‐Chen, Lee, An‐Sheng, Lu, Long‐Sheng, Ke, Liang‐Yin, Chen, Wei‐Yu, Dong, Jian‐Wen, Lu, Jonathan, Chen, Zhenping, Chu, Chih‐Sheng, Chan, Hua‐Chen, Kuzan, Taha Y., Tsai, Ming‐Hsien, Hsu, Wen‐Li, Dixon, Richard A. F., Sawamura, Tatsuya, Chang, Kuan‐Cheng, Chen, Chu‐Huang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052487/
https://www.ncbi.nlm.nih.gov/pubmed/29923368
http://dx.doi.org/10.1111/acel.12792