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Apolipoprotein E region molecular signatures of Alzheimer's disease

Although the APOE region is the strongest genetic risk factor for Alzheimer's diseases (ADs), its pathogenic role remains poorly understood. Elucidating genetic predisposition to ADs, a subset of age‐related diseases characteristic for postreproductive period, is hampered by the undefined role...

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Detalles Bibliográficos
Autores principales: Kulminski, Alexander M., Huang, Jian, Wang, Jiayi, He, Liang, Loika, Yury, Culminskaya, Irina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052488/
https://www.ncbi.nlm.nih.gov/pubmed/29797398
http://dx.doi.org/10.1111/acel.12779