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Use of a gene score of multiple low-modest effect size variants can predict the risk of obesity better than the individual SNPs

BACKGROUND: Obesity is a complex disorder, the development of which is modulated by a multitude of environmental, behavioral and genetic factors. The common forms of obesity are polygenic in nature which means that many variants in the same or different genes act synergistically and affect the body...

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Detalles Bibliográficos
Autores principales: Shabana, Shahid, Saleem Ullah, Hasnain, Shahida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052513/
https://www.ncbi.nlm.nih.gov/pubmed/30021629
http://dx.doi.org/10.1186/s12944-018-0806-5