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Use of a gene score of multiple low-modest effect size variants can predict the risk of obesity better than the individual SNPs
BACKGROUND: Obesity is a complex disorder, the development of which is modulated by a multitude of environmental, behavioral and genetic factors. The common forms of obesity are polygenic in nature which means that many variants in the same or different genes act synergistically and affect the body...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052513/ https://www.ncbi.nlm.nih.gov/pubmed/30021629 http://dx.doi.org/10.1186/s12944-018-0806-5 |