Paired box 8 suppresses tumor angiogenesis and metastasis in gastric cancer through repression of FOXM1 via induction of microRNA-612

BACKGROUND: Paired box 8 (PAX8) has been documented to be downregulated in gastric cancer. However, its biological function in this malignancy is poorly understood. METHODS: In the present work, we investigated the effects of PAX8 overexpression and knockdown on the aggressive phenotype of gastric c...

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Detalles Bibliográficos
Autores principales: Wang, Liyan, Bo, Xiaotong, Zheng, Qinghua, Ge, Wenhong, Liu, Yanhua, Li, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052629/
https://www.ncbi.nlm.nih.gov/pubmed/30021604
http://dx.doi.org/10.1186/s13046-018-0830-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052629/
https://www.ncbi.nlm.nih.gov/pubmed/30021604
http://dx.doi.org/10.1186/s13046-018-0830-3

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