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Incomplete cellular reprogramming of colorectal cancer cells elicits an epithelial/mesenchymal hybrid phenotype

BACKGROUND: Induced pluripotency in cancer cells by ectopic expression of pluripotency-regulating factors may be used for disease modeling of cancers. MicroRNAs (miRNAs) are negative regulators of gene expression that play important role in reprogramming somatic cells. However, studies on the miRNA...

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Detalles Bibliográficos
Autores principales: Hiew, Michele Sook Yuin, Cheng, Han Ping, Huang, Chiu-Jung, Chong, Kowit Yu, Cheong, Soon Keng, Choo, Kong Bung, Kamarul, Tunku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052640/
https://www.ncbi.nlm.nih.gov/pubmed/30025541
http://dx.doi.org/10.1186/s12929-018-0461-1