Abnormal T-Cell Development in the Thymus of Non-obese Diabetic Mice: Possible Relationship With the Pathogenesis of Type 1 Autoimmune Diabetes

Type 1 diabetes (T1D) is an autoimmune disease caused by the destruction of insulin-producing cells in the pancreas, by direct interactions with autoreactive pancreas infiltrating T lymphocytes (PILs). One of the most important animal models for this disease is the non-obese diabetic (NOD) mouse. Al...

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Detalles Bibliográficos
Autores principales: Mendes-da-Cruz, Daniella A., Lemos, Julia P., Passos, Geraldo A., Savino, Wilson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052664/
https://www.ncbi.nlm.nih.gov/pubmed/30050502
http://dx.doi.org/10.3389/fendo.2018.00381

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052664/
https://www.ncbi.nlm.nih.gov/pubmed/30050502
http://dx.doi.org/10.3389/fendo.2018.00381

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