Cargando…
Platelet storage induces accelerated desialylation of platelets and increases hepatic thrombopoietin production
BACKGROUND: Stored platelets undergo deleterious changes, referred to as platelet storage lesions (PSLs), which accelerate the desialylation of platelets and result in their phagocytosis and clearance by hepatic macrophages. Recent studies have reported that Ashwell–Morell receptor binds to desialyl...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052694/ https://www.ncbi.nlm.nih.gov/pubmed/30021591 http://dx.doi.org/10.1186/s12967-018-1576-6 |