Platelet storage induces accelerated desialylation of platelets and increases hepatic thrombopoietin production

BACKGROUND: Stored platelets undergo deleterious changes, referred to as platelet storage lesions (PSLs), which accelerate the desialylation of platelets and result in their phagocytosis and clearance by hepatic macrophages. Recent studies have reported that Ashwell–Morell receptor binds to desialyl...

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Detalles Bibliográficos
Autores principales: Cho, Jooyoung, Kim, Hyunkyung, Song, Jaewoo, Cheong, June-Won, Shin, Jeong Won, Yang, Woo Ick, Kim, Hyun Ok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052694/
https://www.ncbi.nlm.nih.gov/pubmed/30021591
http://dx.doi.org/10.1186/s12967-018-1576-6

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