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Decreased Expression of Sulfatase 2 in the Brains of Alzheimer’s Disease Patients: Implications for Regulation of Neuronal Cell Signaling

BACKGROUND: The human sulfatase 1 (SULF1) and sulfatase 2 (SULF2) genes modulate cell signaling and homeostasis in many tissues. Gene expression analyses have implicated SULF2 in disease pathogenesis, including Alzheimer’s disease (AD), but changes in brain SULF2 expression have not been directly es...

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Detalles Bibliográficos
Autores principales: Roberts, Rosebud O., Kang, Yoo Na, Hu, Chunling, Moser, Catherine D., Wang, Shaoqing, Moore, Michael J., Graham, Rondell P., Lai, Jin-Ping, Petersen, Ronald C., Roberts, Lewis R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052874/
https://www.ncbi.nlm.nih.gov/pubmed/30035253
http://dx.doi.org/10.3233/ADR-170028