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The RNA-Binding Protein HuR Posttranscriptionally Regulates IL-2 Homeostasis and CD4(+) Th2 Differentiation
Posttranscriptional gene regulation by RNA-binding proteins, such as HuR (elavl1), fine-tune gene expression in T cells, leading to powerful effects on immune responses. HuR can stabilize target mRNAs and/or promote translation by interacting with their 3′ untranslated region adenylate and uridylate...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052877/ https://www.ncbi.nlm.nih.gov/pubmed/30035254 http://dx.doi.org/10.4049/immunohorizons.1700017 |