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The RNA-Binding Protein HuR Posttranscriptionally Regulates IL-2 Homeostasis and CD4(+) Th2 Differentiation

Posttranscriptional gene regulation by RNA-binding proteins, such as HuR (elavl1), fine-tune gene expression in T cells, leading to powerful effects on immune responses. HuR can stabilize target mRNAs and/or promote translation by interacting with their 3′ untranslated region adenylate and uridylate...

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Detalles Bibliográficos
Autores principales: Techasintana, Patsharaporn, Ellis, Jason S., Glascock, Jacqueline, Gubin, Matthew M., Ridenhour, Suzanne E., Magee, Joseph D., Hart, Marcia L., Yao, Peng, Zhou, Hao, Whitney, Maryln S., Franklin, Craig L., Martindale, Jennifer L., Gorospe, Myriam, Davis, Wade J., Fox, Paul L., Li, Xiaoxia, Atasoy, Ulus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052877/
https://www.ncbi.nlm.nih.gov/pubmed/30035254
http://dx.doi.org/10.4049/immunohorizons.1700017