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The RNA-Binding Protein HuR Posttranscriptionally Regulates IL-2 Homeostasis and CD4(+) Th2 Differentiation
Posttranscriptional gene regulation by RNA-binding proteins, such as HuR (elavl1), fine-tune gene expression in T cells, leading to powerful effects on immune responses. HuR can stabilize target mRNAs and/or promote translation by interacting with their 3′ untranslated region adenylate and uridylate...
Autores principales: | Techasintana, Patsharaporn, Ellis, Jason S., Glascock, Jacqueline, Gubin, Matthew M., Ridenhour, Suzanne E., Magee, Joseph D., Hart, Marcia L., Yao, Peng, Zhou, Hao, Whitney, Maryln S., Franklin, Craig L., Martindale, Jennifer L., Gorospe, Myriam, Davis, Wade J., Fox, Paul L., Li, Xiaoxia, Atasoy, Ulus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052877/ https://www.ncbi.nlm.nih.gov/pubmed/30035254 http://dx.doi.org/10.4049/immunohorizons.1700017 |
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