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Stabilization benefits of single and multi-layer self-nanoemulsifying pellets: A poorly-water soluble model drug with hydrolytic susceptibility

Solidified self-nanoemulsifying drug delivery systems (SNEDDS) offer strong option to enhance both drug aqueous solubility and stability. The current study was designed to evaluate the potential stabilization benefits of solidifying cinnarizine (CN) liquid SNEDDS into single and multi-layer self-nan...

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Detalles Bibliográficos
Autores principales: Shahba, Ahmad Abdul-Wahhab, Alanazi, Fars Kaed, Abdel-Rahman, Sayed Ibrahim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053139/
https://www.ncbi.nlm.nih.gov/pubmed/30024877
http://dx.doi.org/10.1371/journal.pone.0198469