Evaluation of six months sputum culture conversion as a surrogate endpoint in a multidrug resistant-tuberculosis trial

The emergence of multidrug resistant-tuberculosis (MDR-TB), defined as Mycobacterium tuberculosis strains with in vitro resistance to at least isoniazid and rifampicin, has necessitated evaluation and validation of appropriate surrogate endpoints for treatment response in drug trials for MDR-TB. The...

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Detalles Bibliográficos
Autores principales: Meyvisch, Paul, Kambili, Chrispin, Andries, Koen, Lounis, Nacer, Theeuwes, Myriam, Dannemann, Brian, Vandebosch, An, Van der Elst, Wim, Molenberghs, Geert, Alonso, Ariel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053142/
https://www.ncbi.nlm.nih.gov/pubmed/30024924
http://dx.doi.org/10.1371/journal.pone.0200539

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053142/
https://www.ncbi.nlm.nih.gov/pubmed/30024924
http://dx.doi.org/10.1371/journal.pone.0200539

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