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Murine macrophage TLR2-FcγR synergy via FcγR licensing of IL-6 cytokine mRNA ribosome binding and translation

Macrophages (MØs) are sentinels of the immune system that use pattern recognition receptors such as Toll-like receptors (TLR) to detect invading pathogens and immune receptors such as FcγR to sense the host’s immune state. Crosstalk between these two signaling pathways allows the MØ to tailor the ce...

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Detalles Bibliográficos
Autores principales: Hunt, Danielle, Drake, Lisa A., Drake, James R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053178/
https://www.ncbi.nlm.nih.gov/pubmed/30024985
http://dx.doi.org/10.1371/journal.pone.0200764