The spinal NR2BR/ERK2 pathway as a target for the central sensitization of collagen-induced arthritis pain

OBJECTIVE: Pain management is a huge challenge in the treatment of rheumatoid arthritis (RA), and central sensitization is reportedly involved in the development of pain. The current study was undertaken to explore the possible role of N-methyl-D-aspartate receptors (NMDARs) in the spinal mechanism...

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Detalles Bibliográficos
Autores principales: Xu, Yingming, Zhang, Kui, Miao, Jinlin, Zhao, Peng, Lv, Minghua, Li, Jia, Fu, Xianghui, Luo, Xing, Zhu, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053233/
https://www.ncbi.nlm.nih.gov/pubmed/30024967
http://dx.doi.org/10.1371/journal.pone.0201021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053233/
https://www.ncbi.nlm.nih.gov/pubmed/30024967
http://dx.doi.org/10.1371/journal.pone.0201021

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