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The spinal NR2BR/ERK2 pathway as a target for the central sensitization of collagen-induced arthritis pain
OBJECTIVE: Pain management is a huge challenge in the treatment of rheumatoid arthritis (RA), and central sensitization is reportedly involved in the development of pain. The current study was undertaken to explore the possible role of N-methyl-D-aspartate receptors (NMDARs) in the spinal mechanism...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053233/ https://www.ncbi.nlm.nih.gov/pubmed/30024967 http://dx.doi.org/10.1371/journal.pone.0201021 |