KSHV-induced ligand mediated activation of PDGF receptor-alpha drives Kaposi's sarcomagenesis

Kaposi’s sarcoma (KS) herpesvirus (KSHV) causes KS, an angiogenic AIDS-associated spindle-cell neoplasm, by activating host oncogenic signaling cascades through autocrine and paracrine mechanisms. Tyrosine kinase receptor (RTK) proteomic arrays, identified PDGF receptor-alpha (PDGFRA) as the predomi...

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Detalles Bibliográficos
Autores principales: Cavallin, Lucas E., Ma, Qi, Naipauer, Julian, Gupta, Sachin, Kurian, Mani, Locatelli, Paola, Romanelli, Paolo, Nadji, Mehrdad, Goldschmidt-Clermont, Pascal J., Mesri, Enrique A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053240/
https://www.ncbi.nlm.nih.gov/pubmed/29985958
http://dx.doi.org/10.1371/journal.ppat.1007175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053240/
https://www.ncbi.nlm.nih.gov/pubmed/29985958
http://dx.doi.org/10.1371/journal.ppat.1007175

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