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KSHV-induced ligand mediated activation of PDGF receptor-alpha drives Kaposi's sarcomagenesis

Kaposi’s sarcoma (KS) herpesvirus (KSHV) causes KS, an angiogenic AIDS-associated spindle-cell neoplasm, by activating host oncogenic signaling cascades through autocrine and paracrine mechanisms. Tyrosine kinase receptor (RTK) proteomic arrays, identified PDGF receptor-alpha (PDGFRA) as the predomi...

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Detalles Bibliográficos
Autores principales:	Cavallin, Lucas E., Ma, Qi, Naipauer, Julian, Gupta, Sachin, Kurian, Mani, Locatelli, Paola, Romanelli, Paolo, Nadji, Mehrdad, Goldschmidt-Clermont, Pascal J., Mesri, Enrique A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053240/ https://www.ncbi.nlm.nih.gov/pubmed/29985958 http://dx.doi.org/10.1371/journal.ppat.1007175

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