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The major β-catenin/E-cadherin junctional binding site is a primary molecular mechano-transductor of differentiation in vivo
In vivo, the primary molecular mechanotransductive events mechanically initiating cell differentiation remain unknown. Here we find the molecular stretching of the highly conserved Y654-β-catenin-D665-E-cadherin binding site as mechanically induced by tissue strain. It triggers the increase of acces...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053302/ https://www.ncbi.nlm.nih.gov/pubmed/30024850 http://dx.doi.org/10.7554/eLife.33381 |