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Tunable molecular tension sensors reveal extension-based control of vinculin loading

Molecular tension sensors have contributed to a growing understanding of mechanobiology. However, the limited dynamic range and inability to specify the mechanical sensitivity of these sensors has hindered their widespread use in diverse contexts. Here, we systematically examine the components of te...

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Detalles Bibliográficos
Autores principales: LaCroix, Andrew S, Lynch, Andrew D, Berginski, Matthew E, Hoffman, Brenton D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053308/
https://www.ncbi.nlm.nih.gov/pubmed/30024378
http://dx.doi.org/10.7554/eLife.33927