APOBEC3B and APOBEC mutational signature as potential predictive markers for immunotherapy response in non-small cell lung cancer

Non-small cell lung cancer (NSCLC) is known to carry heavy mutation load. Besides smoking, cytidine deaminase APOBEC3B plays a key role in the mutation process of NSCLC. APOBEC3B is also reported to be upregulated and predicts bad prognosis in NSCLC. However, targeting APOBEC3B high NSCLC is still a...

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Detalles Bibliográficos
Autores principales: Wang, Shixiang, Jia, Mingming, He, Zaoke, Liu, Xue-Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053356/
https://www.ncbi.nlm.nih.gov/pubmed/29695832
http://dx.doi.org/10.1038/s41388-018-0245-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053356/
https://www.ncbi.nlm.nih.gov/pubmed/29695832
http://dx.doi.org/10.1038/s41388-018-0245-9

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