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Microglia permit climbing fiber elimination by promoting GABAergic inhibition in the developing cerebellum

Circuit refinement during postnatal development is finely regulated by neuron–neuron interactions. Recent studies suggest participation of microglia in this process but it is unclear how microglia cooperatively act with neuronal mechanisms. To examine roles of microglia, we ablate microglia by micro...

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Detalles Bibliográficos
Autores principales: Nakayama, Hisako, Abe, Manabu, Morimoto, Chie, Iida, Tadatsune, Okabe, Shigeo, Sakimura, Kenji, Hashimoto, Kouichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053401/
https://www.ncbi.nlm.nih.gov/pubmed/30026565
http://dx.doi.org/10.1038/s41467-018-05100-z