Enzymatic one-step ring contraction for quinolone biosynthesis

The 6,6-quinolone scaffolds on which viridicatin-type fungal alkaloids are built are frequently found in metabolites that display useful biological activities. Here we report in vitro and computational analyses leading to the discovery of a hemocyanin-like protein AsqI from the Aspergillus nidulans...

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Detalles Bibliográficos
Autores principales: Kishimoto, Shinji, Hara, Kodai, Hashimoto, Hiroshi, Hirayama, Yuichiro, Champagne, Pier Alexandre, Houk, Kendall N., Tang, Yi, Watanabe, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053404/
https://www.ncbi.nlm.nih.gov/pubmed/30026518
http://dx.doi.org/10.1038/s41467-018-05221-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053404/
https://www.ncbi.nlm.nih.gov/pubmed/30026518
http://dx.doi.org/10.1038/s41467-018-05221-5

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