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Probing the coordination and function of Fe(4)S(4) modules in nitrogenase assembly protein NifB

NifB is an essential radical S-adenosylmethionine (SAM) enzyme for nitrogenase cofactor assembly. Previous studies show that NifB couples a putative pair of [Fe(4)S(4)] modules (designated K1 and K2) into an [Fe(8)S(9)C] cofactor precursor concomitant with radical SAM-dependent carbide insertion thr...

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Detalles Bibliográficos
Autores principales: Rettberg, Lee A., Wilcoxen, Jarett, Lee, Chi Chung, Stiebritz, Martin T., Tanifuji, Kazuki, Britt, R. David, Hu, Yilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053413/
https://www.ncbi.nlm.nih.gov/pubmed/30026506
http://dx.doi.org/10.1038/s41467-018-05272-8