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PRMT5-mediated regulation of developmental myelination

Oligodendrocytes (OLs) are the myelin-forming cells of the central nervous system. They are derived from differentiation of oligodendrocyte progenitors through a process requiring cell cycle exit and histone modifications. Here we identify the histone arginine methyl-transferase PRMT5, a molecule ca...

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Detalles Bibliográficos
Autores principales: Scaglione, Antonella, Patzig, Julia, Liang, Jialiang, Frawley, Rebecca, Bok, Jabez, Mela, Angeliki, Yattah, Camila, Zhang, Jingxian, Teo, Shun Xie, Zhou, Ting, Chen, Shuibing, Bernstein, Emily, Canoll, Peter, Guccione, Ernesto, Casaccia, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053423/
https://www.ncbi.nlm.nih.gov/pubmed/30026560
http://dx.doi.org/10.1038/s41467-018-04863-9