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Identification of dynamic undifferentiated cell states within the male germline

The role of stem cells in tissue maintenance is appreciated and hierarchical models of stem cell self-renewal and differentiation often proposed. Stem cell activity in the male germline is restricted to undifferentiated A-type spermatogonia (A(undiff)); however, only a fraction of this population ac...

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Detalles Bibliográficos
Autores principales: La, Hue M., Mäkelä, Juho-Antti, Chan, Ai-Leen, Rossello, Fernando J., Nefzger, Christian M., Legrand, Julien M. D., De Seram, Mia, Polo, Jose M., Hobbs, Robin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053434/
https://www.ncbi.nlm.nih.gov/pubmed/30026551
http://dx.doi.org/10.1038/s41467-018-04827-z