Structure of the replication regulator Sap1 reveals functionally important interfaces

The mechanism by which specific protein-DNA complexes induce programmed replication fork stalling in the eukaryotic genome remains poorly understood. In order to shed light on this process we carried out structural investigations on the essential fission yeast protein Sap1. Sap1 was identified as a...

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Detalles Bibliográficos
Autores principales: Jørgensen, Maria M., Ekundayo, Babatunde, Zaratiegui, Mikel, Skriver, Karen, Thon, Geneviève, Schalch, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053445/
https://www.ncbi.nlm.nih.gov/pubmed/30026545
http://dx.doi.org/10.1038/s41598-018-29198-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053445/
https://www.ncbi.nlm.nih.gov/pubmed/30026545
http://dx.doi.org/10.1038/s41598-018-29198-9

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