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Faster growth with shorter antigens can explain a VSG hierarchy during African trypanosome infections: a feint attack by parasites

The parasitic African trypanosome, Trypanosoma brucei, evades the adaptive host immune response by a process of antigenic variation that involves the clonal switching of variant surface glycoproteins (VSGs). The VSGs that come to dominate in vivo during an infection are not entirely random, but disp...

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Detalles Bibliográficos
Autores principales: Liu, Dianbo, Albergante, Luca, Newman, T. J., Horn, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053454/
https://www.ncbi.nlm.nih.gov/pubmed/30026531
http://dx.doi.org/10.1038/s41598-018-29296-8