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Synchronized mesenchymal cell polarization and differentiation shape the formation of the murine trachea and esophagus

Tube morphogenesis is essential for internal-organ development, yet the mechanisms regulating tube shape remain unknown. Here, we show that different mechanisms regulate the length and diameter of the murine trachea. First, we found that trachea development progresses via sequential elongation and e...

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Detalles Bibliográficos
Autores principales: Kishimoto, Keishi, Tamura, Masaru, Nishita, Michiru, Minami, Yasuhiro, Yamaoka, Akira, Abe, Takaya, Shigeta, Mayo, Morimoto, Mitsuru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053463/
https://www.ncbi.nlm.nih.gov/pubmed/30026494
http://dx.doi.org/10.1038/s41467-018-05189-2