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Increased IL-22- and IL-17A-Producing Mucosal-Associated Invariant T Cells in the Peripheral Blood of Patients With Ankylosing Spondylitis

The IL-23/T helper 17 (Th17) axis plays an important role in joint inflammation in ankylosing spondylitis (AS). Conventional CD4(+) Th17 cells are a major source of IL-17A. IL-22 is another cytokine implicated in AS pathophysiology and is produced by Th17 and Th22 cells. In this study, we aimed to a...

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Detalles Bibliográficos
Autores principales: Toussirot, Éric, Laheurte, Caroline, Gaugler, Béatrice, Gabriel, Damien, Saas, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053500/
https://www.ncbi.nlm.nih.gov/pubmed/30057583
http://dx.doi.org/10.3389/fimmu.2018.01610