Mutations of Recombinant Aquaporin-4 Antibody in the Fc Domain Can Impair Complement-Dependent Cellular Cytotoxicity and Transplacental Transport

Maternal antibodies provide protection for the developing fetus. Transplacental transport of pathogenic autoantibodies might pose a risk for the developing fetus. The transport of antibodies across the placenta to the fetal circulation occurs through the neonatal Fc salvage receptor (FcRn). During g...

Descripción completa

Detalles Bibliográficos
Autores principales: Mader, Simone, Brimberg, Lior, Soltys, John N., Bennett, Jeffrey L., Diamond, Betty
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053506/
https://www.ncbi.nlm.nih.gov/pubmed/30057582
http://dx.doi.org/10.3389/fimmu.2018.01599

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053506/
https://www.ncbi.nlm.nih.gov/pubmed/30057582
http://dx.doi.org/10.3389/fimmu.2018.01599

Ejemplares similares