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Coupling of polymerase and carrier lipid phosphatase prevents product inhibition in peptidoglycan synthesis

Peptidoglycan (PG) is an essential component of the bacterial cell wall that maintains the shape and integrity of the cell. The PG precursor lipid II is assembled at the inner leaflet of the cytoplasmic membrane, translocated to the periplasmic side, and polymerized to glycan chains by membrane anch...

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Detalles Bibliográficos
Autores principales: Hernández-Rocamora, Víctor M., Otten, Christian F., Radkov, Atanas, Simorre, Jean-Pierre, Breukink, Eefjan, VanNieuwenhze, Michael, Vollmer, Waldemar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053597/
https://www.ncbi.nlm.nih.gov/pubmed/30046664
http://dx.doi.org/10.1016/j.tcsw.2018.04.002