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Coupling of polymerase and carrier lipid phosphatase prevents product inhibition in peptidoglycan synthesis
Peptidoglycan (PG) is an essential component of the bacterial cell wall that maintains the shape and integrity of the cell. The PG precursor lipid II is assembled at the inner leaflet of the cytoplasmic membrane, translocated to the periplasmic side, and polymerized to glycan chains by membrane anch...
Autores principales: | Hernández-Rocamora, Víctor M., Otten, Christian F., Radkov, Atanas, Simorre, Jean-Pierre, Breukink, Eefjan, VanNieuwenhze, Michael, Vollmer, Waldemar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053597/ https://www.ncbi.nlm.nih.gov/pubmed/30046664 http://dx.doi.org/10.1016/j.tcsw.2018.04.002 |
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