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Tumoral BRD4 expression in lymph node-negative breast cancer: association with T-bet+ tumor-infiltrating lymphocytes and disease-free survival
BACKGROUND: We previously observed that T-bet+ tumor-infiltrating T lymphocytes (T-bet+ TILs) in primary breast tumors were associated with adverse clinicopathological features, yet favorable clinical outcome. We identified BRD4 (Bromodomain-Containing Protein 4), a member of the Bromodomain and Ex...
Autores principales: | Lee, Minji, Tayyari, Farnoosh, Pinnaduwage, Dushanthi, Bayani, Jane, Bartlett, John M. S., Mulligan, Anna Marie, Bull, Shelley B., Andrulis, Irene L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053709/ https://www.ncbi.nlm.nih.gov/pubmed/30029633 http://dx.doi.org/10.1186/s12885-018-4653-6 |
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