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In silico prediction of novel residues involved in amyloid primary nucleation of human I56T and D67H lysozyme
BACKGROUND: Amyloidogenic proteins are most often associated with neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s disease, and Huntington’s disease, but there are more than two dozen human proteins known to form amyloid fibrils associated with disease. Lysozyme is an antimicrobia...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053722/ https://www.ncbi.nlm.nih.gov/pubmed/30029603 http://dx.doi.org/10.1186/s12900-018-0088-1 |