Regulation of tNOX expression through the ROS-p53-POU3F2 axis contributes to cellular responses against oxaliplatin in human colon cancer cells

BACKGROUND: Oxaliplatin belongs to the platinum-based drug family and has shown promise in treating cancer by binding to DNA to induce cytotoxicity. However, individual patients show diverse therapeutic responses toward oxaliplatin due to yet-unknown underlying mechanisms. We recently established th...

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Detalles Bibliográficos
Autores principales: Chen, Huei-Yu, Islam, Atikul, Yuan, Tien-Ming, Chen, Shi-Wen, Liu, Pei-Fen, Chueh, Pin Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053734/
https://www.ncbi.nlm.nih.gov/pubmed/30029680
http://dx.doi.org/10.1186/s13046-018-0837-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053734/
https://www.ncbi.nlm.nih.gov/pubmed/30029680
http://dx.doi.org/10.1186/s13046-018-0837-9

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