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Regulation of tNOX expression through the ROS-p53-POU3F2 axis contributes to cellular responses against oxaliplatin in human colon cancer cells

BACKGROUND: Oxaliplatin belongs to the platinum-based drug family and has shown promise in treating cancer by binding to DNA to induce cytotoxicity. However, individual patients show diverse therapeutic responses toward oxaliplatin due to yet-unknown underlying mechanisms. We recently established th...

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Detalles Bibliográficos
Autores principales:	Chen, Huei-Yu, Islam, Atikul, Yuan, Tien-Ming, Chen, Shi-Wen, Liu, Pei-Fen, Chueh, Pin Ju
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053734/ https://www.ncbi.nlm.nih.gov/pubmed/30029680 http://dx.doi.org/10.1186/s13046-018-0837-9

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