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Genomic alterations accompanying tumour evolution in colorectal cancer: tracking the differences between primary tumours and synchronous liver metastases by whole-exome sequencing

BACKGROUND: Colorectal cancer (CRC) patients with metastatic disease can become cured if neoadjuvant treatment can enable a resection. The search for predictive biomarkers is often performed on primary tumours tissue. In order to assess the effectiveness of tailored treatment in regard to the primar...

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Detalles Bibliográficos
Autores principales: Mogensen, M. B., Rossing, M., Østrup, O., Larsen, P. N., Heiberg Engel, P. J., Jørgensen, L. N., Hogdall, E. V., Eriksen, J., Ibsen, P., Jess, P., Grauslund, M., Nielsen, H. J., Nielsen, F. C., Vainer, B., Osterlind, K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053835/
https://www.ncbi.nlm.nih.gov/pubmed/30029640
http://dx.doi.org/10.1186/s12885-018-4639-4