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Real-time detection of histone deacetylase activity with a small molecule fluorescent and spectrophotometric probe
Histone deacetylases (HDACs) are central players in transcription regulation and important targets in cancer treatment. Activity assays are critical tools for the study of the function and regulation of these enzymes, as well as for the screening of potential inhibitors. We report a small-molecule p...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054043/ https://www.ncbi.nlm.nih.gov/pubmed/30090264 http://dx.doi.org/10.1039/c5sc02704g |