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Lab on a single microbead: an ultrasensitive detection strategy enabling microRNA analysis at the single-molecule level
Detection of a single nucleic acid molecule is of great significance for both fundamental biochemistry studies and clinical diagnostics. By using microRNA (miRNA) as a model target, herein, we have developed a single-microbead-based sensing (SMBS) platform, which simply enables the detection of miRN...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054045/ https://www.ncbi.nlm.nih.gov/pubmed/30090237 http://dx.doi.org/10.1039/c5sc02641e |