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Whole-genome amplification in double-digest RADseq results in adequate libraries but fewer sequenced loci

Whole-genome amplification by multiple displacement amplification (MDA) is a promising technique to enable the use of samples with only limited amount of DNA for the construction of RAD-seq libraries. Previous work has shown that, when the amount of DNA used in the MDA reaction is large, double-dige...

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Detalles Bibliográficos
Autores principales: de Medeiros, Bruno A. S., Farrell, Brian D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054070/
https://www.ncbi.nlm.nih.gov/pubmed/30038852
http://dx.doi.org/10.7717/peerj.5089