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Antidepressant effects of aqueous extract of saffron and its effects on CREB, P-CREB, BDNF, and VGF proteins in rat cerebellum

OBJECTIVE: The role of BDNF (brain-derived neurotrophic factor), CREB (cAMP response element binding) and VGF neuropeptide has been proved in antidepressant activity of long term saffron administration in the rat hippocampus. In this study we evaluated the role of these proteins in antidepressant ac...

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Detalles Bibliográficos
Autores principales: Asrari, Najmeh, Yazdian-Robati, Rezvan, Abnous, Khalil, Razavi, BiBi Marjan, Rashednia, Mrazieh, Hasani, Faezeh Vahdati, Hosseinzadeh, Hossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Pharmacopuncture Institute (KPI) 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054076/
https://www.ncbi.nlm.nih.gov/pubmed/30151303
http://dx.doi.org/10.3831/KPI.2018.21.005