High-throughput sequencing of the T-cell receptor repertoire: pitfalls and opportunities

T-cell specificity is determined by the T-cell receptor, a heterodimeric protein coded for by an extremely diverse set of genes produced by imprecise somatic gene recombination. Massively parallel high-throughput sequencing allows millions of different T-cell receptor genes to be characterized from...

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Detalles Bibliográficos
Autores principales: Heather, James M, Ismail, Mazlina, Oakes, Theres, Chain, Benny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054146/
https://www.ncbi.nlm.nih.gov/pubmed/28077404
http://dx.doi.org/10.1093/bib/bbw138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054146/
https://www.ncbi.nlm.nih.gov/pubmed/28077404
http://dx.doi.org/10.1093/bib/bbw138

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