The activity of a mammalian proline-rich peptide against Gram-negative bacteria, including drug-resistant strains, relies on a nonmembranolytic mode of action

BACKGROUND: A peptide of 2,733 Da named SP-E, previously isolated from pig saliva and already described for its antifungal activity and absence of toxicity against mammalian cells, is characterized by a high content of proline residues (70% of entire sequence), that confer structural features probab...

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Detalles Bibliográficos
Autores principales: Ciociola, Tecla, Giovati, Laura, Giovannelli, Angela, Conti, Stefania, Castagnola, Massimo, Vitali, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054295/
https://www.ncbi.nlm.nih.gov/pubmed/30046246
http://dx.doi.org/10.2147/IDR.S165179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054295/
https://www.ncbi.nlm.nih.gov/pubmed/30046246
http://dx.doi.org/10.2147/IDR.S165179

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