Sarpagan bridge enzyme has substrate-controlled cyclization and aromatization modes

Cyclization reactions that create complex polycyclic scaffolds are hallmarks of alkaloid biosynthetic pathways. We present the discovery of three homologous cytochromes P450 from three monoterpene indole alkaloid-producing plants (Rauwolfia serpentina, Gelsemium sempervirens and Catharanthus roseus)...

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Detalles Bibliográficos
Autores principales: Dang, Thu-Thuy T, Franke, Jakob, Teto Carqueijeiro, Inês Soares, Langley, Chloe, Courdavault, Vincent, O’Connor, Sarah E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054303/
https://www.ncbi.nlm.nih.gov/pubmed/29942076
http://dx.doi.org/10.1038/s41589-018-0078-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054303/
https://www.ncbi.nlm.nih.gov/pubmed/29942076
http://dx.doi.org/10.1038/s41589-018-0078-4

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