Mechanotransduction in talin through the interaction of the R8 domain with DLC1

The mechanical unfolding of proteins is a cellular mechanism for force transduction with potentially broad implications in cell fate. Despite this, the mechanism by which protein unfolding elicits differential downstream signalling pathways remains poorly understood. Here, we used protein engineerin...

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Detalles Bibliográficos
Autores principales: Haining, Alexander William M., Rahikainen, Rolle, Cortes, Ernesto, Lachowski, Dariusz, Rice, Alistair, von Essen, Magdalena, Hytönen, Vesa P., del Río Hernández, Armando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Short Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054372/
https://www.ncbi.nlm.nih.gov/pubmed/30028837
http://dx.doi.org/10.1371/journal.pbio.2005599

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054372/
https://www.ncbi.nlm.nih.gov/pubmed/30028837
http://dx.doi.org/10.1371/journal.pbio.2005599

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